发明名称 CRTH2受容体モジュレータとしてのシクロアルキル縮合テトラヒドロキノリン
摘要 The invention provides certain cycloalkyl-fused tetrahydroquinolines of the Formula (I), and their pharmaceutically acceptable salts and esters, wherein R1, R2, R7, R8a, E, Y, Z, n, u, and t are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions associated with uncontrolled or inappropriate stimulation of CRTH2 function.
申请公布号 JP5629403(B2) 申请公布日期 2014.11.19
申请号 JP20140515975 申请日期 2012.06.14
申请人 发明人
分类号 C07D221/16;A61K31/473;A61K31/501;A61K31/506;A61K31/5377;A61P11/00;A61P11/02;A61P11/06;A61P29/00;A61P37/08;A61P43/00;C07D401/04;C07D401/06;C07D401/10;C07D401/12;C07D405/06;C07D405/12;C07D409/06;C07D409/12;C07D413/04;C07D413/06;C07D413/12;C07D417/06;C07D417/10;C07D417/12 主分类号 C07D221/16
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