发明名称 |
NEUROMEDIN U DERIVATIVE |
摘要 |
<p>An object of the present invention is to provide a novel anorectic agent. Another object of the invention is to provide an NMU derivative which exhibits a high anorectic effect even when administered in a usual manner, for example, peripherally. These objects can be achieved by the compound represented by formula (I)
or a salt thereof. In formula (I), Y represents a polypeptide containing an amino acid sequence set forth in SEQ ID NO.: 1 wherein 1 to 4 amino acids are substituted; X represents a methoxypolyethylene glycol; X' is absent or represents a methoxypolyethylene glycol; and a moiety represented by formula: La-Lb-[Lc] j represents a linker.</p> |
申请公布号 |
EP2418213(B1) |
申请公布日期 |
2014.11.19 |
申请号 |
EP20100761456 |
申请日期 |
2010.04.08 |
申请人 |
TAKEDA PHARMACEUTICAL COMPANY LIMITED |
发明人 |
ASAMI, TAIJI;INOOKA, HIROSHI;NISHIZAWA, NAOKI |
分类号 |
C07K7/06;A61K38/00;A61P3/04;C07K7/02;C07K14/575 |
主分类号 |
C07K7/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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