| 发明名称 |
EFFICIENT PROTEIN EXPRESSION IN VIVO USING MODIFIED RNA (MOD-RNA) |
| 摘要 |
Aspects of the invention described herein relate to synthetic, modified RNAs and their use in vivo to modulate gene expression. Aspects of the invention further relate to the use of these synthetic, modified RNAs in myocytes, cardiomyoctes, and tumors. |
| 申请公布号 |
EP2694660(A4) |
申请公布日期 |
2014.11.19 |
| 申请号 |
EP20120767300 |
申请日期 |
2012.03.12 |
| 申请人 |
THE GENERAL HOSPITAL CORPORATION;CHILDREN'S MEDICAL CENTER CORPORATION |
发明人 |
CHIEN, KENNETH, R.;PTASZEK, LEON, M.;LUI, OI LAN;ZANGI, LIOR;EBINA, WATARU;ROSSI, DERRICK J. |
| 分类号 |
C12N15/87;A61K31/7115;A61K48/00;A61P35/00;A61P43/00;C12N15/11 |
主分类号 |
C12N15/87 |
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