发明名称 |
Process for the preparation of dronedarone |
摘要 |
The subject of the present invention is a novel process for the preparation of N-[2-n-butyl-3-{4-[(3-dibutylamino)propoxy]benzoyl}-1-benzofuran-5-yl]methanesulfonamide of formula I:;
and the new intermediates of the preparation process. |
申请公布号 |
US8889734(B2) |
申请公布日期 |
2014.11.18 |
申请号 |
US201313905624 |
申请日期 |
2013.05.30 |
申请人 |
SANOFI |
发明人 |
Friesz Antal;Dombrady Zsolt;Csatarine Nagy Mariann |
分类号 |
A61K31/343;C07D307/78;C07D307/80;C07D307/82 |
主分类号 |
A61K31/343 |
代理机构 |
Scully, Scott, Murphy & Presser, P.C. |
代理人 |
Scully, Scott, Murphy & Presser, P.C. |
主权项 |
1. A compound of formula II: wherein X is chloro-, bromo- or iodo atom, hydroxyl- or activated hydroxyl group. |
地址 |
Paris FR |