发明名称 Process for the preparation of dronedarone
摘要 The subject of the present invention is a novel process for the preparation of N-[2-n-butyl-3-{4-[(3-dibutylamino)propoxy]benzoyl}-1-benzofuran-5-yl]methanesulfonamide of formula I:; and the new intermediates of the preparation process.
申请公布号 US8889734(B2) 申请公布日期 2014.11.18
申请号 US201313905624 申请日期 2013.05.30
申请人 SANOFI 发明人 Friesz Antal;Dombrady Zsolt;Csatarine Nagy Mariann
分类号 A61K31/343;C07D307/78;C07D307/80;C07D307/82 主分类号 A61K31/343
代理机构 Scully, Scott, Murphy & Presser, P.C. 代理人 Scully, Scott, Murphy & Presser, P.C.
主权项 1. A compound of formula II: wherein X is chloro-, bromo- or iodo atom, hydroxyl- or activated hydroxyl group.
地址 Paris FR