Mammary artery derived cells and methods of use in tissue repair and regeneration

摘要

An isolated mammalian internal mammary artery-derived cell is disclosed. Furthermore, methods of isolating the mammalian internal mammary artery-derived cell are disclosed. The cell is useful in tissue engineering technologies, specifically in vascular tissue engineering.

主权项

1. An in vitro cell culture comprising:
a culture vessel; a culture medium comprising internal mammary artery-derived cell growth medium; and cells derived from a mammalian internal mammary artery and capable of self-renewal and expansion in culture, wherein said cells are positive for the expression of cell-surface marker HLA-1 and negative for expression of each one of cell-surface markers CD 10, CD31, CD34, CD45, CD133, CD141 and KDR/Flk-1, and wherein said cells are plated in the culture vessel with the culture medium.