| 主权项 |
1. A method of assessing a patient's risk of suffering from a disease using indicator substances −n from body fluids comprising the steps of:
a) recording, with a computer, measured values for the indicator substances n in an n-dimensional system of coordinates represented by (X1, X2 . . . Xn), b) calculating, by the computer, in the n-dimensional system of coordinates, curves or areas representing polynomials of an mth order for an indicator substance k (k consisting arbitrarily of 1, . . . , n) as a function of the remaining n−1 indicator substances (1, . . . , k−1, k+1, . . . , n), the curves or areas being of identical functional values y for a function y=f (X1, X2, . . . , Xn), the function y being a measure of risk calculated using a kernel density method of (X1, X2, . . . , Xn)=Dd(X1, X2, . . . , Xn)/(Dd(X1, X2, . . . , Xn)+Dn(X1, X2, . . . , Xn)) where Dd(X1, X2, . . . , Xn) is a first density for the probability distribution of diseased patients from a study population and Dn(X1, X2, . . . , Xn) is a second density for the probability distribution of non-diseased patients from the study population, and c) assigning a value corresponding to a specific risk y1 of having a disease based on a location of the measured values within the n-dimensional system of coordinates, the specific risk y1 being between functional values represented by two next adjacent curves or areas of a subgroup of the curves or areas. |
