| 发明名称 | Treatment of osteoarthritis and pain | ||
| 摘要 | The present invention relates to the treatment of osteoarthritis and pain using IL-1α and IL-1β binding proteins, including anti-IL-1α and anti-IL-1β antibodies and engineered multivalent and multispecific IL-1α and IL-1β binding proteins. | ||
| 申请公布号 | US8889130(B2) | 申请公布日期 | 2014.11.18 |
| 申请号 | US201213369177 | 申请日期 | 2012.02.08 |
| 申请人 | Abbvie Inc. | 发明人 | Kamath Rajesh V. |
| 分类号 | A61K39/395;A61K39/40;C07K16/24;C07K16/00;A61K39/00 | 主分类号 | A61K39/395 |
| 代理机构 | Lathrop & Gage LLP | 代理人 | Lathrop & Gage LLP ;Velema, Esq. James H.;Dini Peter |
| 主权项 | 1. A method for treating osteoarthritis in an individual suffering from the osteoarthritis, the method comprising the step of administering to the individual: a Dual Variable Domain Immunoglobulin (DVD-Ig) binding protein that binds both IL-1α and IL-1β, thereby treating the osteoarthritis in the individual. | ||
| 地址 | North Chicago IL US | ||