| 发明名称 | Acetylsalicylic acid salts | ||
| 摘要 | Novel betaine salts of acetylsalicylic acid, namely 4-trimethylammoniobutanoate acetylsalicylic acid addition salt (gamma-butyrobetaine acetylsalicylate), L-carnitine acetylsalicylic acid addition salt and 3-(trimethylammonioamino)propanoate (meldonium) acetylsalicylic acid addition salt. Use of meldonium acetylsalicylate as antiplatelet agent for treating various pathologies induced by platelet aggregation, anti-inflammatory and antihyperlipidemic agent. | ||
| 申请公布号 | US8889902(B2) | 申请公布日期 | 2014.11.18 |
| 申请号 | US201013377926 | 申请日期 | 2010.06.21 |
| 申请人 | Tetra, SIA | 发明人 | Kalvins Ivars;Birmans Anatolijs;Veveris Maris;Lebedevs Antons;Misnovs Anatolijs |
| 分类号 | C07C65/10;C07C69/157;C07C229/22;C07C229/12;C07C243/40;A61K31/616 | 主分类号 | C07C65/10 |
| 代理机构 | Hueschen and Sage | 代理人 | Hueschen and Sage |
| 主权项 | 1. A compound which is a 3-(trimethylammonioamino)propanoate (meldonium) acetylsalicylic acid addition salt, wherein the compound exhibits essentially the following X-ray pattern having peaks at 2Θ values 5.19, 13.22, 13.82, 14.20, 14.95, 15.36, 15.93, 18.11, 18.97, 19.74, 21.02, 22.15, 23.15, 23.65, 24.31, 25.28, 26.18, 26.58, 27.73, 28.36±0.2°. | ||
| 地址 | Riga LV | ||