PIRAZOLOPIRROLIDINAS COMO INIBIDORES DE GAMA SECRETASE, COMPOSIÇÃO FARMACÊUTICA COMPREENDENDO AS MESMAS E USO DOS REFERIDOS COMPOSTOS

摘要

The invention provides compounds of Formula I wherein A, Y, R1, R1a, R2, and R2a are as described in the specification. Compounds of Formula I are useful in treating and/or preventing cognitive disorders, such as Alzheimer's disease. The invention also encompasses pharmaceutical compositions comprising compounds of Formula I, methods of preparing compounds of Formula I, and methods of treating cognitive disorders, such as Alzheimer's disease.