N-(2-(HETARYL)ARYL)ARYLSULFONAMIDES AND N-(2- (HETARYL)HETARYL)ARYLSULFONAMIDES N-(2-()) N-(2-())

摘要

Compounds are provided that act as potent antagonists of the CCR9 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR9. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR9-mediated diseases, and as controls in assays for the identification of CCR9 antagonists.