发明名称 |
1,1,1-TRIFLUORO-2-HYDROXYPROPYL COMPOUNDS 111--2- |
摘要 |
The present invention relates to compounds of formula I wherein R.sup.1a to R.sup.1e and R.sup.2 to R.sup.5 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are glucocorticoid receptor antagonists useful for the treatment and/or prevention of diseases such as diabetes, dyslipidemia, obesity, hypertension, cardiovascular diseases, adrenal imbalance or depression. |
申请公布号 |
HK1162032(A1) |
申请公布日期 |
2014.11.14 |
申请号 |
HK20120102493 |
申请日期 |
2012.03.13 |
申请人 |
F.HOFFMANN LA ROCHE AG |
发明人 |
HUNZIKER, DANIEL;LERNER, CHRISTIAN;MUELLER, WERNER;OBST SANDER, ULRIKE;PFLIEGER, PHILIPPE;WALDMEIER, PIUS |
分类号 |
C07D;A61K |
主分类号 |
C07D |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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