Compuestos heterociclicos no aromaticos sustituidos; composicion farmaceutica que los comprende; y metodo para tratar un cancer seleccionado de glioma (glioblastoma), leucemia mielogena aguda, melanoma, cancer de pulmon de celula no pequeña (nsclc), colangiocarcinomas y sindromes mielodisplasicos (mds), entre otros.

摘要

Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.