发明名称 |
ANTI-VIRULENCE COMPOSITIONS AND METHODS |
摘要 |
A method of reducing the virulence of a bacterium that expresses accessory gene regulator A (AgrA) includes administering to the bacterium an amount of AgrA antagonist effective to inhibit the synthesis of one or more virulence factors by the bacterium. |
申请公布号 |
US2014336258(A1) |
申请公布日期 |
2014.11.13 |
申请号 |
US201414445713 |
申请日期 |
2014.07.29 |
申请人 |
Case Western Reserve University |
发明人 |
Shoham Menachem |
分类号 |
C07C49/83;A61K31/12;A61K31/192;C07C309/44;A61K31/185;C07C65/24;C07C49/84;A61K45/06 |
主分类号 |
C07C49/83 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Cleveland OH US |