| 摘要 |
A process for the manufacture of alkylamino alkylene phosphonic acids is disclosed. In detail, a specific phosphonate is reacted with an agent selected to yield an alkylamino moiety substituted by a radical selected from OH, OR', NH2, NHR′, N(R′)2, NH, N, S, S—S and SH in aqueous alkaline medium having a pH of 8 or higher at a temperature of 0° C. or higher. |
| 主权项 |
1. A process for the manufacture of alkylamino alkylene phosphonic acids having the formula:
U—[X—N (W) (ZPO3M2)]s by reacting a phosphonic acid compound having the formula:
Y—X—N(W) (ZPO3M2) with a precursor of the moiety: U the structural elements having the following meaning: Y is selected from: substituents the conjugated acid of which have a pKa equal to or smaller than 4.0; X is selected from C2-C50 linear, branched, cyclic or aromatic hydrocarbon chains, optionally substituted by a C1-C12 linear, branched, cyclic, or aromatic group, (which chain and/or which group can be) optionally substituted by COOH, F, R20 [A-O]x-wherein R2 is a C1-C50 linear, branched, cyclic or aromatic hydrocarbon chain, and SR′ moieties, wherein R′ is a C1-C50 linear, branched, cyclic or aromatic hydrocarbon chain, optionally substituted by C1-C12 linear, branched, cyclic or aromatic hydrocarbon groups, (said chains and/or groups can be) optionally substituted by COOH, F, and SR′; and [A-O]x-A wherein A is a C2-C9 linear, branched, cyclic or aromatic hydrocarbon chain and x is an integer from 1 to 200; Z is a C1-C6 alkylene chain; M is selected from H and C1-C20 linear, branched, cyclic or aromatic hydrocarbon chains; W is selected from H, ZPO3M2 and [V-N (K)]nK, wherein V is selected from: a C2-C50 linear, branched, cyclic or aromatic hydrocarbon chain, optionally substituted by C1-C12 linear, branched, cyclic or aromatic groups, (which chains and/or groups can be) optionally substituted by OH, COOH, F, OR′, R2O[A-O]x-wherein R2 is a C1-C50 linear, branched, cyclic or aromatic hydrocarbon chain, and SR′ moieties; and from [A-O]x-A wherein A is a C2-C9 linear, branched, cyclic or aromatic hydrocarbon chain and x is an integer from 1 to 200; K is ZPO3M2 or H and n is an integer from 0 to 200; and U is a moiety selected from OH and OR′ wherein R′ is as defined above; s is 1, in aqueous medium, having a pH of 8 or more, at a temperature of 0° C. or higher. |
