| 摘要 |
PROBLEM TO BE SOLVED: To provide a CXCR4 antagonistic peptide that inhibits infection of CXCR4 depending viruses such as HIV-I, and provide a CXCR4 tropic virus infection inhibitor and an anti-HIV agent containing, as an active ingredient, the peptide.SOLUTION: The invention relates to peptides containing the following amino acid sequence: LVRYTKKVPQVSTPTL (ALB408-423) and its biologically active fragments, and/or variants, and/or derivatives, especially amidated, acetylated, sulfated, phosphorylated and/or glycosylated derivatives, and peptides obtainable by multiple synthesis which have the biological activity of ALB408-423; containing a specific amino acid sequence consisting of from 8 to 16 residues. |
