BIOCONJUGATE VACCINES MADE IN PROKARYOTIC CELLS

摘要

Provided herein are prokaryotic cells capable of producing bioconjugates comprising glycosylated proteins. Also provided herein are compositions comprising such bioconjugates and/or comprising the saccharide moieties of such bioconjugates, as well as methods of vaccinating subjects using such compositions.

主权项

1. A bioconjugate comprising (i) a carrier protein and a monosaccharide; (ii) a carrier protein and a disaccharide; or (iii) a carrier protein and a trisaccharide.