METHODS AND PRODUCTS FOR REAWAKENING RETROCYCLINS

摘要

Products and methods are provided for the restoring the endogenous expression of theta-defensins, such as retrocyclin-1, in mamallian cells. The present invention also includes products and methods for inhibiting sexually transmitted virus entry, e.g., HIV-1 virus entry, into a mammalian cell via, for example, administering to a subject an amount of a read-through mediating agent sufficient to induce exogenous expression of an amount of retrocyclin nonapeptides in the mammalian cell.

主权项

1. A pharmaceutical composition for inhibiting HIV-1 cell entry comprising an amount of a read-through mediating agent effective to induce expression of a retrocyclin polypeptide in a mammalian cell.