| 发明名称 |
RADIOLABELED BIOMARKERS FOR OSTEOCLAST ACTIVATION AND RELATED METHODS THEREOF |
| 摘要 |
The present invention provides biomarkers that find use as imaging agents within nuclear medicine applications (e.g., PET imaging and SPECT imaging). In particular, the present invention provides methods for identifying and characterizing osteoclast activation within subjects with radiolabeled cathepsin K inhibitors. |
| 申请公布号 |
US2014336503(A1) |
申请公布日期 |
2014.11.13 |
| 申请号 |
US201414266458 |
申请日期 |
2014.04.30 |
| 申请人 |
The Regents of the University of Michigan |
发明人 |
Kilbourn Michael R.;Kozloff Kenneth;Rodnick Melissa E. |
| 分类号 |
A61K51/04;A61B6/00;A61B6/03 |
主分类号 |
A61K51/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition comprising a radiolabeled compound selected from the group consisting of: wherein the radiolabeled compound is radiolabeled with either 11C, 18F or 123I; wherein the radiolabeled compound is a cathepsin K inhibitor. |
| 地址 |
Ann Arbor MI US |
