发明名称 METHOD FOR MANUFACTURING 4-BENZYL-1-METHYL-6-OXABICYCLO[3,2,0]HEPTANE DERIVATIVE AND METHOD FOR MANUFACTURING AZOLE DERIVATIVE
摘要 In order to manufacture a higher yield of a 4-benzyl-1-methyl-6-oxabicyclo[3,2,0]heptane derivative, the present invention is a method for manufacturing a compound represented by General Formula (I) which includes a step for reducing a compound represented by General Formula (II) using a hydride-type reducing agent in an aprotic solvent having an amide bond.
申请公布号 US2014336389(A1) 申请公布日期 2014.11.13
申请号 US201214357058 申请日期 2012.11.05
申请人 Kureha Corporation 发明人 Kanno Hisashi
分类号 C07D405/06;C07D249/08 主分类号 C07D405/06
代理机构 代理人
主权项 1. A method for manufacturing a compound represented by General Formula (I) below, the method including a step for reducing a compound represented by General Formula (II) below using a hydride-type reducing agent in an aprotic solvent having an amide bond or a mixed solvent including the aprotic solvent; in General Formula (I), Y represents a halogen atom, an alkyl group having 1 to 4 carbon atoms, a haloalkyl group having 1 to 4 carbon atoms, an alkoxy group having 1 to 4 carbon atoms, a haloalkoxy group having 1 to 4 carbon atoms, or a phenyl group, m represents an integer from 0 to 5, Y being the same or different when m is an integer equal to or greater than 2, and A represents a nitrogen atom or a methine group; in General Formula (II), Y, m and A are the same as Y, m and A in General Formula (I), respectively, R3 represents an alkyl group having 1 to 3 carbon atoms, a haloalkyl group having 1 to 3 carbon atoms, a substitutable phenyl group, or a substitutable naphthyl group.
地址 Chuo-ku Tokyo JP