| 主权项 |
1. A compound represented by the following general formula (I), or a pharmaceutically acceptable salt thereof: wherein Ar is an aromatic carbocyclic ring or a heterocyclic ring; Ar2 is represented by any one of the following rings these rings may have a substituent, andthe substituent is selected from the group consisting of acetamido, aminocarbonyl, benzyl, benzyloxy, a halogen, hydroxyl-lower alkyl, lower alkyl, lower alkoxy-lower alkyl, phenoxy, phenyl, a formyl group, a cyano group, a cyanoalkyl group, a hydroxyiminomethyl group, a hydroxyamidino group, an amino group, an aminoalkyl group, an alkylaminoalkyl group, a dialkylaminoalkyl group, lower alkoxy, and trifluoro-methoxy; R2 and R3 are independently selected from the group consisting of lower alkyl, lower alkoxy, trifluoromethyl, a halogen, hydroxy, a hydroxyl-lower alkyl group, amino, alkylamino, dialkylamino, cyano, and nitro; R4 is an amino acid residue bonded to C(O) through a nitrogen atom of the amino acid; R5 is a cyanoalkyl group or -CD3, or is represented by any one of the following substituents R6 is hydrogen, a lower alkyl group, a cyanoalkyl group, a hydroxyalkyl group, or an alkoxyalkyl group, or is represented by any one of the following substituents R7 and R8 are each a cyanoalkyl group, a formyl group, an alkoxycarbonyl group, or a hydroxyiminomethyl group; R9 is hydrogen or a lower alkyl group; m is 0, 1, 2, 3, or 4; p is 0, 1, or 2; and s is 0, 1, or 2. |
