发明名称 |
FIMBRIAE TYPE OF PROPHYROMONAS GULAE |
摘要 |
The present invention has as its object to provide a process for determining the degree of pathogenicity of infecting bacterial strains in the case of canine periodontal disease.;The present inventors found that Porphyromonas gulae is a major pathogen of canine periodontal disease, and demonstrated that the fimA genes encoding FimA (fimbrillin) protein which constitute fimbriae of this bacterium are classified into three major groups, and that each of the groups is correlated with the pathogenicity of this bacterium as a pathogenic bacterial of periodontal disease. Thus the inventors completed the present invention. |
申请公布号 |
US2014335121(A1) |
申请公布日期 |
2014.11.13 |
申请号 |
US201214364810 |
申请日期 |
2012.12.13 |
申请人 |
School Corporation, Azabu Veterinary Medicine Educational Institution ;Osaka University |
发明人 |
Asai Fumitoshi;Kato Yukio;Shirai Mitsuyuki;Murakami Masaru;Nakano Kazuhiko;Nomura Ryota |
分类号 |
C07K14/195;C12Q1/68 |
主分类号 |
C07K14/195 |
代理机构 |
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代理人 |
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主权项 |
1. A partial peptide of FimA (fimbrillin) protein from a Porphyromonas gulae strain classified as group C, which comprises the amino acid sequence of SEQ ID NO: 22. |
地址 |
Sagamihara-shi, Kanagawa JP |