COMPOSITIONS AND METHODS FOR DETECTING AND DETERMINING A PROGNOSIS FOR PROSTATE CANCER

摘要

The present disclosure provides methods of detecting and determining the aggressiveness of prostate cancer. These methods can be used to determine whether or not a patient needs a biopsy as well as guide treatment selection.

主权项

1. An assay method for selectively measuring mRNA and protein expression in a blood sample and urine sample from a subject, the method comprising:
(a) selectively measuring the expression level of a gene's mRNA from the urine sample by quantitative reverse transcription polymerase chain reaction (RT-PCR); (b) selectively measuring the expression level of the gene's mRNA from the blood sample by quantitative RT-PCR; and (c) selectively measuring the expression level of the gene's protein from the blood sample by immunological detection.