发明名称 |
ACC INHIBITORS AND USES THEREOF |
摘要 |
The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same. Specifically, bicyclic heteroaryl derivatives containing a imidazole, thiazole or oxazole fused to a pyridinone, pyrimidinone or pyrimidindione are provided. These compounds have therapeutic utility toward treating an ACC enzyme mediated disorder such as obesity in a subject, upon administration in an effective amount to said subject. |
申请公布号 |
CA2911932(A1) |
申请公布日期 |
2014.11.13 |
申请号 |
CA20142911932 |
申请日期 |
2014.05.08 |
申请人 |
NIMBUS APOLLO, INC. |
发明人 |
GREENWOOD, JEREMY ROBERT;HARRIMAN, GERALDINE C.;BORG, GEORGE;MASSE, CRAIG E. |
分类号 |
C07D513/04;A61K31/4355;A61K31/4365;A61K31/519;A61P3/00;A61P3/04;A61P3/06;C07D471/04;C07D487/04;C07D498/04 |
主分类号 |
C07D513/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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