发明名称 Histone deacetylase inhibitors based on derivatives of tricyclic polyhydroacridine and analogs possessing fused saturated five- and seven-membered rings
摘要 The present invention refers to compounds of formula (I): as well as to a method for their preparation, pharmaceutical compositions comprising the same, and use thereof for the treatment and/or chemoprevention of cancer hematological malignancy, proliferative diseases, neurological disorders and immunological disorders.
申请公布号 EP2801569(A1) 申请公布日期 2014.11.12
申请号 EP20130382170 申请日期 2013.05.09
申请人 IKERCHEM, S.L.;UNIVERSIDAD DEL PAIS VASCO 发明人 COSSIO MORA, FERNANDO PEDRO;VARA SALAZAR, YOSU ION;MASDEU MARGALEF, MARÍA DEL CARMEN;ALCALÀ CAFFARENA, MARÍA REMEDIOS;VILLAFRUELA CÁNEVA, SERGIO;OTAEGUI ANSA, DORLETA;ALDABA ARÉVALO, ENEKO;ZUBIA OLASCOAGA, AIZPEA;SAN SEBASTIÁN LARZABAL, EIDER
分类号 C07D219/10;A61K31/435;A61P19/00;C07D221/06;C07D471/04 主分类号 C07D219/10
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