NOVEL OXYNTOMODULIN DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR TREATING OBESITY COMPRISING THE SAME

摘要

The present invention relates to a novel peptide and a composition for preventing or treating obesity which includes the peptide, as an active ingredient, having greater activity for a receptor of glucagon-like peptide-1 and a receptor of glucagon than a natural type oxyntomodulin. The novel peptide of the present invention has effects of facilitating fat decomposition and inhibiting gastric emptying without side effects and enables food intake to be reduced which are not seen in the natural type oxyntomodulin. In addition, the novel peptide of the present invention has greater effects of activating the receptor compared to the natural type oxyntomodulin, thus can be widely used for treating obesity in a safe manner.