Electrical brain stimulation in gamma band

摘要

This disclosure describes techniques for delivering electrical stimulation to the brain of a patient at a frequency greater than a selected frequency. The techniques may reestablish gamma frequency band activity within the brain of a patient, and thus improve the patient's movements and cognitive states. In one example, the disclosure is directed to a method that includes selecting a frequency within a gamma frequency band and delivering electrical stimulation at a frequency greater than the selected frequency.

主权项

1. A method comprising:
selecting a frequency within a gamma frequency band, wherein the selected frequency is one of a patient-specific frequency or a representative frequency; delivering electrical stimulation, via one or more electrodes, at a frequency greater than the selected frequency; in response to delivering the electrical stimulation, measuring an amplitude of a rhythm in at least one of the gamma frequency band and a beta frequency band; determining, by one or more processors whether the measured amplitude is indicative of a desired gamma frequency band activity having been re-induced, and based on whether the measured amplitude is indicative of the desired gamma frequency band activity having been re-induced, determining whether to deliver additional electrical stimulation, via the one or more electrodes, at the frequency greater than the selected frequency, and in response to a determination to deliver additional electrical stimulation at the frequency greater than the selected frequency, delivering, via the one or more electrodes, the additional electrical stimulation.