Apparatuses and methods using the role of ventricular electrical delay to predict left ventricular remodeling with cardiac resynchronization therapy

摘要

A system comprises a cardiac signal sensing circuit and a processor circuit. The cardiac signal sensing circuit is configured to sense a cardiac signal segment using a set of electrodes connectable to the cardiac signal sensing circuit. The processor circuit is communicatively coupled to the cardiac signal sensing circuit and includes a peak detector circuit. The peak detector circuit is configured to identify, in the cardiac signal segment, a fiducial indicative of ventricular activation that is local to at least one electrode of the first set of electrodes. The fiducial includes a first large positive or negative peak greater than a specified percentage of a maximum peak of the first cardiac signal segment. The processor circuit is configured to provide an indication of local ventricular activation to at least one of a user or process.

主权项

1. A system comprising:
a first cardiac signal sensing circuit configured to sense a first cardiac signal segment using a first set of electrodes connectable to the first cardiac signal sensing circuit, wherein the first cardiac signal segment is sensed over a cardiac cycle; a processor circuit communicatively coupled to the first cardiac signal sensing circuit, wherein the processor circuit includes a peak detector circuit configured to:
identify, in the first cardiac signal segment, a maximum peak of a cardiac cycle of the first cardiac signal segment,identify, within the same cardiac cycle, a first positive or negative peak having an amplitude that is greater than a specified percentage of the identified maximum peak, andindicate the identified positive or negative peak as a fiducial indicative of ventricular activation that is local to at least one electrode of the first set of electrodes, wherein the processor circuit is configured to provide an indication of local ventricular activation to at least one of a user or process.