| 发明名称 | Adjuvant | ||
| 摘要 | Methods and immunogenic compositions for generating an immune response against Marburg virus are provided. The immunogenic composition includes antigens obtained from a Marburg viral strain in combination with an oleanolic acid triterpene adjuvant. | ||
| 申请公布号 | US8883170(B2) | 申请公布日期 | 2014.11.11 |
| 申请号 | US200812203272 | 申请日期 | 2008.09.03 |
| 申请人 | Western Illinois University Research Foundation;Southern Research Institute | 发明人 | Pathak Ashish Kumar;Pathak Vibha;May Richard D. |
| 分类号 | A61K39/12;C07J17/00;C07H15/256;A61K39/00 | 主分类号 | A61K39/12 |
| 代理机构 | Fitch, Even, Tabin & Flannery, LLP | 代理人 | Fitch, Even, Tabin & Flannery, LLP |
| 主权项 | 1. An adjuvant having a structure wherein R1 is an oligosaccharide having a structure selected from the group consisting of wherein R4 is H and y is 1 to 6, R2 is NH(CH2)xCH3, wherein x is about 3 to about 23, and R3 is H or OH. | ||
| 地址 | Macomb IL US | ||