发明名称 COMPOSTO MACROCÍCLICO
摘要 The present invention provides a novel class of compounds that have the activity of inhibiting HSP90 enzyme and are useful as anti-cancer agents or such, and compounds that are useful as synthetic intermediates thereof. Specifically, the present invention provides compounds represented by the following formula (1), and pharmaceutically acceptable salts thereof: wherein X, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , L 1 , L 2 , and L 3 are as defined in the specification.
申请公布号 BRPI0808524(A2) 申请公布日期 2014.11.11
申请号 BR2008PI08524 申请日期 2008.02.29
申请人 CHUGAI SEIYAKU KABUSHIKI KAISHA 发明人 NOBUO SHIMMA;TAKUO TSUKUDA;HIROSHI KOYANO;ATSUSHI SUDA;TADAKATSU HAYASE;KIHITO HADA;KEN-ICHI KAWASAKI;SUSUMU KOMIYAMA;NAOMI ONO;TOSHIKAZU YAMAZAKI;RYOICHI SAITOH;MASAMI KOHCHI;KIYOSHI HASEGAWA
分类号 C07D497/08;A61K31/529;A61K31/53;A61K31/5377;A61P1/16;A61P9/10;A61P11/00;A61P13/12;A61P17/00;A61P17/02;A61P19/02;A61P21/00;A61P25/00;A61P25/28;A61P29/00;A61P31/00;A61P35/00;A61P35/02;A61P37/02;A61P37/06;A61P43/00;C07D513/08;C07D513/18;C07D513/20;C07D515/08 主分类号 C07D497/08
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