Ion exchange resin treated to control swelling

摘要

The present invention provides a method and composition are provided for loading one or more drugs in a solution onto one or more ion exchange resin particles to form a drug-loaded resin particle. The drug-loaded resin particle is a sustained-release coated layered pharmaceutical drug-ion exchange resin having a one or more pharmaceutically active drugs applied directly to a non-equilibrated ion exchange resin to form a drug-resin complex. The drug-resin complex then coated is shelf stable.

主权项

1. A method of forming a coated pharmaceutical drug-ion exchange resin composition, comprising the steps of:
dissolving the pharmaceutically active drug in a solvent to form a solution or suspending the pharmaceutically active drug in a vehicle to form a suspension; and applying the solution or suspension directly to the ion exchange resin to form the coated pharmaceutical drug-ion exchange resin composition, wherein the method is carried out without equilibrating the ion exchange resin to ionically bind with the pharmaceutically active drug.