| 摘要 |
The invention relates to 2-amino-2-phenyl-alkanol-derived esters of general formula (I), where: Rforms, with Rmid the nitrogen and carbon atoms to which they arc respectively attached, a 4- to 7-membered heterocyclic compound, optionally substituted, in position α of the nitrogen atom, by radicals Rand Rthat, separately from each other, can be a hydrogen or a Straight or branched alkyl (1 to ); and Ris Η or a HO-O-CHR-OCORradical for which Ris a hydrogen or a straight or branched alkyl (1 to ); and Ris an alkyl optionally substituted by benzyloxycarbonylamino, acylamino, or by the residue of an amino acid, or is a heterocyclic compound; or Ris a straight or branched alkyl (1 to ), or an alkyl (2 to ) substituted by OH, alkoxy, alkylthio, NH, alkylamino, or dialkylamino optionally forming, with the nitrogen atom to which they are attached, a 5- or 6-membered heterocyclic compound, assuming that said substituted alkyl is straight or branched and comprises at least 2 C between >N-Rand the substituent, wherein, unless otherwise mentioned, alkyl or acyl are straight or branched (1 to ), in the R or S forms thereof or in the form of the mixtures thereof, as well as the pharmaceutically acceptable salts thereof, if present., (I) |
