| 摘要 |
PROBLEM TO BE SOLVED: To provide use of one or more anti-connexin peptides or anti-connexin peptidomimetic agents for prevention and/or alleviation of adhesion.SOLUTION: A composition, an article, a device and a method for therapy and/or prevention of adhesion in human and nonhuman animals are provided. The present invention also generally relates to use of one or more anti-connexin polynucleotides (for example, alpha-1 connexin oligodeoxynucleotide and the like) in combination with one or more anti-connexin peptides, anti-connexin peptidomimetic agents (for example, alpha-1 anti-connexin peptide, alpha-1 anti-connexin peptidomimetic agent) and/or gap junction modification agents (for example, a hemichannel-closing compound comprising a connexin carboxyl terminal polypeptide and a connexin phosphorylated compound) for prevention and/or alleviation of adhesion. |
