发明名称 TECHNIQUE FOR ISOLATING/CULTURING COLORECTAL EPITHELIAL STEM CELL, AND TECHNIQUE FOR TRANSPLANTING COLORECTAL EPITHELIUM EMPLOYING SAID TECHNIQUE
摘要 It is an object of the present invention to provide a culture medium for in vitro culture of a colorectal epithelial stem cell or the like, a method of in vitro culturing a colorectal epithelial stem cell or the like using the culture medium, a prophylactic or therapeutic agent for a bowel disease containing a colorectal epithelial stem cell or the like cultured by the method, a method of administrating, i.e., transplanting a colorectal epithelial stem cell or the like cultured by the method to a bowel disease patient, and a method of isolating a colorectal epithelial stem cell or the like. The culture medium for in vitro culture of a colorectal epithelial stem cell and/or a colorectal epithelial cell characteristically contains serum albumin, Wnt3a, and r-spondin-1.
申请公布号 US2014328808(A1) 申请公布日期 2014.11.06
申请号 US201214352517 申请日期 2012.10.26
申请人 National University Corporation Tokyo Medical and Dental University 发明人 Watanabe Mamoru;Nakamura Tetsuya
分类号 C12N5/074 主分类号 C12N5/074
代理机构 代理人
主权项 1. A culture medium for in vitro culture of a colorectal epithelial stem cell and/or a colorectal epithelial cell, comprising serum albumin, Wnt3a, and r-spondin-1.
地址 Bunkyo-ku, Tokyo JP