发明名称 |
TECHNIQUE FOR ISOLATING/CULTURING COLORECTAL EPITHELIAL STEM CELL, AND TECHNIQUE FOR TRANSPLANTING COLORECTAL EPITHELIUM EMPLOYING SAID TECHNIQUE |
摘要 |
It is an object of the present invention to provide a culture medium for in vitro culture of a colorectal epithelial stem cell or the like, a method of in vitro culturing a colorectal epithelial stem cell or the like using the culture medium, a prophylactic or therapeutic agent for a bowel disease containing a colorectal epithelial stem cell or the like cultured by the method, a method of administrating, i.e., transplanting a colorectal epithelial stem cell or the like cultured by the method to a bowel disease patient, and a method of isolating a colorectal epithelial stem cell or the like. The culture medium for in vitro culture of a colorectal epithelial stem cell and/or a colorectal epithelial cell characteristically contains serum albumin, Wnt3a, and r-spondin-1. |
申请公布号 |
US2014328808(A1) |
申请公布日期 |
2014.11.06 |
申请号 |
US201214352517 |
申请日期 |
2012.10.26 |
申请人 |
National University Corporation Tokyo Medical and Dental University |
发明人 |
Watanabe Mamoru;Nakamura Tetsuya |
分类号 |
C12N5/074 |
主分类号 |
C12N5/074 |
代理机构 |
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代理人 |
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主权项 |
1. A culture medium for in vitro culture of a colorectal epithelial stem cell and/or a colorectal epithelial cell, comprising serum albumin, Wnt3a, and r-spondin-1. |
地址 |
Bunkyo-ku, Tokyo JP |