摘要 |
The present invention relates to nucleic acid fragments encoding amino acid sequences for metal-handling enzymes, such as copper chaperones, high affinity potassium transporters, metallothioneins, aluminium-stress induced 5 proteins, cadmium resistance proteins, copper transporting ATPases, blue copper binding proteins, copper transporters, cadmium induced proteins, zinc transporters, zinc binding proteins and phytochelatin synthases, in plants and the use thereof for modifying metal handling in plants, including modification of plant heavy metal detoxification; modification of plant tolerance to metals such as 10 copper, zinc, cadmium and aluminium; modification of plant capacity for accumulation or hyper-accumulation of metals such as cadmium; modification of plant intracellular metal trafficking pathways such as intracellular copper-delivery systems for the delivery of copper to ethylene receptors and transport of copper from senescing leaves; modification of plant uptake of nutrients such as 15 potassium, zinc, manganese and copper; modification of plant capacity of essential heavy metal homeostasis; modification of plant metabolism and/or development associated with heavy metals; and modification of plant responses to toxic or suboptimal levels of metals. |