发明名称 |
Prevention of disulfide bond reduction during recombinant production of polypeptides |
摘要 |
The invention concerns methods and means for preventing the reduction of disulfide bonds during the recombinant production of disulfide-containing polypeptides. In particular, the invention concerns the prevention of disulfide bond reduction during harvesting of disulfide-containing polypeptides, including antibodies, from recombinant host cell cultures. |
申请公布号 |
AU2008275229(B2) |
申请公布日期 |
2014.11.06 |
申请号 |
AU20080275229 |
申请日期 |
2008.07.08 |
申请人 |
GENENTECH, INC. |
发明人 |
KAO, YUNG-HSIANG;LAIRD, MICHAEL W.;SCHMIDT, MELODY TREXLER;WONG, RITA L.;HEWITT, DANIEL P. |
分类号 |
C07K1/00;C07K14/00 |
主分类号 |
C07K1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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