| 摘要 |
The present application discloses complexes useful as catalysts for organic chemical synthesis including hydrogenation and dehydrogenation of unsaturated compounds or dehydrogenation of substrates. The range of hydrogenation substrate compounds includes esters, lactones, oils and fats, resulting in alcohols, diols, and triols as reaction products. The catalysts of current application can be used to catalyze a hydrogenation reaction under solvent free conditions. The present catalysts also allow the hydrogenation to proceed without added base, and it can be used in place of the conventional reduction methods employing hydrides of the main-group elements. Furthermore, the catalysts of the present application can catalyze a dehydrogenation reaction under homogenous and/or acceptorless conditions. As such, the catalysts provided herein can be useful in substantially reducing cost and improving the environmental profile of manufacturing processes for variety of chemicals. |
| 主权项 |
1. A compound of Formula Iwherein
L is a phosphine (PR1R2), a sulfide (SR1), or a carbene group (CR1R2); each Y is independently a C, N or S atom, wherein at least two Y's are C; the dotted lines simultaneously or independently represent single or double bonds, wherein when a single bond is present the carbon atom or atoms bound to R4, R5 or both, are additionally bound to an H; R1 and R2 are each independently H, or a C1-C20 linear alkyl, a C3-C20 branched alkyl, a C3-C8 cycloalkyl, a C2-C8 alkenyl, a C5-C20 aryl, each of which may be optionally substituted, or OR or NR2; or when taken together, R1 and R2 can together with L to which they are bound form a saturated or partially saturated ring; R3 is H, or a C1-C8 linear alkyl, a C3-C8 branched alkyl, a C3-C8 cyclic alkyl, a C2-C8 alkenyl, or a C5-C8 aryl, each of which may be optionally substituted; R4 is H a C3-C8 linear alkyl, C3-C8 cyclic alkyl, a C2-C8 alkenyl, or a C5-C8 aryl, each of which may be optionally substituted; or R3 and R4 can join together to form a saturated heterocycle; R5 is H, a linear C1-C8 alkyl, a branched C3-C8 alkyl, a cyclic C3-C8 alkyl, a C2-C8 alkenyl, or a C5-C8 aryl, each of which can be optionally substituted; or R5 and R4 can join together to form a saturated heterocycle; each X is independently H, a linear C1-C8 alkyl, a branched C3-C8 alkyl, a cyclic C3-C8 alkyl, a C2-C8 alkenyl, or a C5-C8 aryl, each of which can be optionally substituted, or OR, F, Cl, Br, I or NR2; or when taken together, two of the X groups can together form an optionally substituted, saturated, partially saturated, aromatic or heteroaromatic ring; R is H, a C1-C20 linear alkyl, a C3-C20 branched alkyl, a C3-C8 cycloalkyl, a C2-C8 alkenyl, or a C5-C8 aryl, each of which may be optionally substituted; each n and m is independently 1 or 2; k is 1 or 2; and z is 0 or 1. |
