| 发明名称 |
Diagnostic and Therapeutic Methods and Their Application in Amyotrophic Lateral Sclerosis (ALS) |
| 摘要 |
The present invention provides a method of treating, delaying the onset, delaying progression of, reducing the incidence of or reducing the severity of amyotrophic lateral sclerosis in a subject, the method comprising administering to a subject an agent, which interferes with IgG-A2BG2 expression, IgG-A2BG2 function or IgG-A2BG2 interaction with CD16 in said subject. |
| 申请公布号 |
US2014328824(A1) |
申请公布日期 |
2014.11.06 |
| 申请号 |
US201214361806 |
申请日期 |
2012.12.04 |
| 申请人 |
BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY |
发明人 |
Porgador Angel |
| 分类号 |
A61K38/47;C07K16/42;G01N33/68;A61K31/428 |
主分类号 |
A61K38/47 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating, delaying the onset, delaying progression of, reducing the incidence of or reducing the severity of amyotrophic lateral sclerosis in a subject, said method comprising administering to a subject an agent, which interferes with IgG-A2BG2 expression, IgG-A2BG2 function or IgG-A2BG2 interaction with CD16 in said subject. |
| 地址 |
Beer Sheva IL |
