| 发明名称 |
PEPTIDES AND NANOPARTICLES FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS |
| 摘要 |
Provided herein are peptides and nanoparticles conjugates thereof useful for the treatment of diseases and disorders mediated by GIPC/synectin, such as cancer. |
| 申请公布号 |
US2014329760(A1) |
申请公布日期 |
2014.11.06 |
| 申请号 |
US201314060932 |
申请日期 |
2013.10.23 |
| 申请人 |
Mayo Foundation for Medical Education and Research ;Trustees of Dartmouth College |
发明人 |
Mukhopadhyay Debabrata;Mukherjee Priyabrata;Spaller Mark |
| 分类号 |
C07K7/06 |
主分类号 |
C07K7/06 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A bioconjugate comprising a metal nanoparticle bound to at least one peptide, wherein said peptide has an amino acid sequence of Formula II:II(SEQ ID NO: 2)X1-X2-X3-X4-X5-X6-X7-X8 wherein: X1 is lysine; X2 is glutamic acid; X3 is arginine; X4 is leucine; X5 is threonine; X6 is serine or cysteine; X7 is aspartic acid; and X8 is glycine or alanine, or a pharmaceutically acceptable salt thereof. |
| 地址 |
Rochester MN US |
