发明名称 |
PLANT VIRAL EXPRESSION VECTORS AND USE OF SAME FOR GENERATING GENOTYPIC VARIATIONS IN PLANT GENOMES |
摘要 |
A method of generating genotypic variation in a genome of a plant is disclosed. The method comprising introducing into the plant at least one viral expression vector encoding at least one chimeric nuclease which comprises a DNA binding domain, a nuclease and a localization signal to a DNA-containing organelle, wherein the DNA binding domain mediates specific targeting of the nuclease to the genome of the plant, thereby generating genotypic variation in the genome of the plant. |
申请公布号 |
US2014331360(A1) |
申请公布日期 |
2014.11.06 |
申请号 |
US201414341999 |
申请日期 |
2014.07.28 |
申请人 |
Danziger Innovations Ltd. ;Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. |
发明人 |
VAINSTEIN Alexander;Zuker Amir |
分类号 |
C12N15/82 |
主分类号 |
C12N15/82 |
代理机构 |
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代理人 |
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主权项 |
1. A plant viral expression vector comprising a pTRV backbone and comprising a nucleic acid sequence encoding a heterologous polypeptide, said nucleic acid sequence being devoid of the 2b sequence as set forth in SEQ ID NO: 43. |
地址 |
Moshav Mishmar HaShiva IL |