发明名称 |
VIRUCIDAL SMALL MOLECULE AND USES THEREOF |
摘要 |
In an embodiment of the present disclosure there is provided a method of inactivating enveloped DNA virus particles in a biological sample. In an embodiment, such a method comprises contacting the biological sample with an effective amount of an antiviral composition comprising PD 404,182 In some embodiments, the DNA virus is the Herpes Simplex virus-1 (HSV-1) or the Herpes Simplex Virus-2 (HSV-2). In another embodiment of the present disclosure, there is provided a method of treating, preventing, or reducing a viral infection caused by an enveloped DNA virus in a subject in need thereof. In yet another embodiment, there is provided a method of preventing transmission of a viral infection to a subject in need thereof. In an embodiment, such a method comprises contacting a mucus membrane of the subject with a topical formulation comprising an effective amount of PD 404,182 in combination with a pharmaceutically acceptable carrier |
申请公布号 |
US2014328795(A1) |
申请公布日期 |
2014.11.06 |
申请号 |
US201314023437 |
申请日期 |
2013.09.10 |
申请人 |
Chen Zhilei;Chockalingam Karrupiah;Chamoun-Emanuelli Ana M.;Simeon Rudo;Bobardt Michael;Gallay Philippe |
发明人 |
Chen Zhilei;Chockalingam Karrupiah;Chamoun-Emanuelli Ana M.;Simeon Rudo;Bobardt Michael;Gallay Philippe |
分类号 |
A61K31/542;A61K45/06 |
主分类号 |
A61K31/542 |
代理机构 |
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代理人 |
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主权项 |
1. A method of inactivating virus particles in a biological sample, the method comprising: contacting the biological sample with an effective amount of an antiviral composition comprising PD 404,182, wherein the virus particle is an enveloped virus, wherein the enveloped virus is a DNA virus. |
地址 |
College Station TX US |