POROUS PARTICLES FOR LIQUID CHROMATOGRAPHY AND PROCESSES FOR THE PREPARATION THEREOF

摘要

Superficially porous silica particles are provided as well as a one-pot process for making the superficially porous particles, the process comprising hydrolyzing and condensing a silica precursor comprising a functional group to form superficially porous particles, the superficially porous particles comprising silica microparticles having silica nanoparticles bound to the surface of the microparticles. The nanoparticles provide a porous outer layer on the microparticles. The superficially porous particles are useful as a stationary phase in liquid chromatography and allow for fast mass transfer and separation of samples

主权项

1. A one-pot process for making superficially porous silica particles, the process comprising hydrolyzing and condensing a silica precursor comprising a functional group to form superficially porous silica particles, the superficially porous silica particles comprising substantially non-porous silica microparticles having silica nanoparticles bound to the surface of the microparticles.