SYSTEMS AND METHODS ENABLING HIGH-THROUGHPUT, REAL TIME DETECTION OF ANALYTES

摘要

System and methods for detecting analytes are provided. The system includes a plasmonic interferometer with a first surface having a first and second scattering element and an aperture disposed between the first scattering element and the second scattering element. A first distance between the aperture and the first scattering element and a second distance between the aperture and the second scattering element are selected to provide interference of light at the slit. The system also includes a light source for illuminating the first surface of the plasmonic interferometer, a detector positioned for detecting light transmitted through the aperture, and a sample holder for disposing a sample to be analyzed onto the first surface of the plasmonic interferometer.

主权项

1. A system for detecting an analyte comprising:
a plasmonic interferometer, the plasmonic interferometer comprising a first surface having a first scattering element and a second scattering element and an aperture disposed between the first scattering element and the second scattering element to define a first distance between the aperture and the first scattering element and a second distance between the aperture and the second scattering element, wherein the first and second distances are selected to provide interference of light at the aperture; a light source for illuminating the first surface of the plasmonic interferometer; a detector positioned for detecting light transmitted through the aperture; and a sample holder for disposing a sample to be analyzed onto the first surface of the plasmonic interferometer.