METHOD AND APPARATUS FOR CORRECTIVE SECONDARY SACCADES ANALYSIS WITH VIDEO OCULOGRAPHY SYSTEM

摘要

A video oculography system for calculation and display of Corrective Secondary Saccades Analysis is disclosed. A method for Objective Diagnostics of at least one of traumatic brain injury, Internuclear Opthalmopligia, Ocular Lateral Pulsion, Progressive Supernuclear Palsy And Glissades comprises the steps of using a VOG system to calculate corrective saccades. The video oculography based system for the subject is configured to collect eye images of the patient in excess of 60 hz and configured to resolve eye movements smaller than at least 3 degrees of motion. The video oculography based system collects eye movement data wherein at least one fixation target is presented to the subject in a defined position configured to yield a voluntary saccadic eye response from at least one eye of the patient. The latency, amplitude, accuracy and velocity of each respective corrective saccade and totals latency and accuracy is calculated.

主权项

1. A method of objective diagnostic of traumatic brain injury in a subject comprising the steps of:
Providing a video oculography based system for the subject with the video oculograpghy system configured to collect eye images of the patient in excess of 60 hz and configured to resolve eye movements smaller than at least 3 degrees of motion; Collecting eye data with the video oculography based system wherein at least one fixation target is presented to the subject in a defined position configured to yield a voluntary saccadic eye response from at least one eye of the patient, wherein the initial saccadic eye response to the target is a primary saccadic response and subsequent saccadic eye responses to the target are corrective saccadic eye responses to the target; Calculating corrective saccade measurements from the eye data including at least one of:
i) total number of corrective saccades associated with the subject's eye movement to each fixation target presented to the subject;ii) first corrective saccade latency associated with the subject's first corrective saccade eye movement to each fixation target presented to the subject;iii) first corrective saccade amplitude associated with the subject's first corrective saccade eye movement to each fixation target presented to the subject;iv) first corrective saccade accuracy associated with the subject's first corrective saccade eye movement to each fixation target presented to the subject;v) first corrective saccade velocity associated with the subject's first corrective saccade eye movement to each fixation target presented to the subject;vi) ratio of first corrective saccade amplitude to a primary saccade amplitude associated with the subject's eye movement to each fixation target presented to the subject; andvii) ratio of total of corrective saccade amplitudes to the primary saccade amplitude associated with the subject's eye movement to each fixation target presented to the subject; and Utilizing a comparison between at least one calculated corrective saccade measurement and a baseline for said calculated corrective saccade measurement as an indication of the presence of traumatic brain injury in a subject.