发明名称 |
FUNCTIONAL GENOMICS USING CRISPR-CAS SYSTEMS, COMPOSITIONS, METHODS, KNOCK OUT LIBRARIES AND APPLICATIONS THEREOF |
摘要 |
<p>The present invention generally relates to compositions, methods applications and screens used in functional genomics that focus on gene function in a ceil and that may use vector systems and other aspects related to Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)- Cas systems and components thereof. Provided are vectors and vector systems, some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Also provided are methods of directing CRISPR complex formation in eukaryotic cells and methods for utilizing the CRJSPR-Cas system.</p> |
申请公布号 |
WO2014093701(A9) |
申请公布日期 |
2014.11.06 |
申请号 |
WO2013US74800 |
申请日期 |
2013.12.12 |
申请人 |
THE BROAD INSTITUTE, INC.;MASSACHUSETTS INSTITUTE OF TECHNOLOGY;ZHANG, FENG;SANJANA, NEVILLE, ESPI;SHALEM, OPHIR |
发明人 |
ZHANG, FENG;SANJANA, NEVILLE, ESPI;SHALEM, OPHIR |
分类号 |
C12N15/63;C12N15/10;C40B40/08 |
主分类号 |
C12N15/63 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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