COMPOSITIONS USEFUL FOR THE TREATMENT OF VIRAL DISEASES

摘要

The present invention is directed to compositions comprising inhibitors of hepatitis C virus (HCV) protease and one or more additional therapeutically effective agents. Uses of such compositions as HCV inhibitors and methods of treating infection by HCV by administration of such compositions are also disclosed.

主权项

1. A pharmaceutical composition comprising:
(i) a pharmaceutically acceptable carrier; (ii) a compound selected from Table 1:TABLE 11234567891011121314or a pharmaceutically acceptable salt thereof; and (iii) one or more Primary Additional Therapeutic Agents, or a pharmaceutically acceptable salt thereof, wherein the one or more Primary Additional Therapeutic Agents are selected from the group consisting of HCV protease inhibitors, HCV polymerase inhibitors, HCV NS4A inhibitors and HCV NS5A inhibitors, wherein the one or more Primary Additional Therapeutic Agents do not comprise a Compound of Table 1, and wherein the amounts of the Compound of Table 1 and the one or more Primary Additional Therapeutic Agents are together effective to treat HCV infection in a patient, such that when the one or more Primary Additional Therapeutic Agents comprise an HCV NS5A inhibitor, the HCV NS5A inhibitor is not one of the following compounds:or a pharmaceutically acceptable salt thereof.