COMBINATION THERAPY OF AN AFUCOSYLATED CD20 ANTIBODY WITH A CD79b ANTIBODY-DRUG CONJUGATE
摘要
The present invention is directed to the combination therapy of an afucosylated anti-CD20 antibody with a CD79b antibody-drug conjugate for the treatment of cancer, especially to the combination therapy of CD20 expressing cancers with an afucosylated humanized B-Ly1 antibody and a CD79b antibody-drug conjugate.
申请公布号
WO2014177615(A2)
申请公布日期
2014.11.06
申请号
WO2014EP58827
申请日期
2014.04.30
申请人
F. HOFFMANN-LA ROCHE AG;GENENTECH, INC.;HOFFMANN-LA ROCHE INC.
发明人
KLEIN, CHRISTIAN;LANG, SABINE;POLSON, ANDREW G.;UMANA, PABLO