发明名称 |
CULICINAE MOSQUITO TRA-2 RNA INTERFERENCE TECHNIQUE TO GENETICALLY PRODUCE MALENESS POPULATION |
摘要 |
The present invention develops a novel method for controlling mosquito populations. Culicinae mosquitoes carrying one or more loci of transformant Tra-2 RNAi constructs which target to mosquito Transformer-2 locus in respective or none respective Culicinae mosquitoes. Tra-2 sequences used to assemble Tra-2 RNAi recombinant constructs are Tra-2 gene sequences of Culicinae mosquitoes and can be derived from endogenous or exogenous sequences. The Tra-2 RNAi expression is conditional, wherein the expression causing a knockdown effect into the endogenous Tra-2 gene results in mortality of X (m) chromosome bearing sperms and produces maleness mosquito population in the nature environmental of the species. |
申请公布号 |
US2014331342(A1) |
申请公布日期 |
2014.11.06 |
申请号 |
US201114356978 |
申请日期 |
2011.12.29 |
申请人 |
Hoang Duong Thanh;Hoang Kim Phuc |
发明人 |
Hoang Duong Thanh;Hoang Kim Phuc |
分类号 |
C12N15/113;A01K67/033 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Hanoi City VN |