| 主权项 |
1. A method of determining if administration of 17β-estradiol or testosterone is needed in an individual having a Huntington's Disease (HD) gene with a number of CAG repeats between about 36 and about 120, the method comprising:
a. assessing a level of 17β-estradiol, free testosterone, or total testosterone in the individual to determine if the level is below a normal level; and b. comparing the level to a normal level of about 100 pg/ml for 17β-estradiol, to a normal level of about 20 pg/ml for free testosterone, or to a normal level of about 300 ng/dL for total testosterone, thereby determining if the level is below a normal level; wherein a level below a normal level indicates a need to administer an amount of 17β-estradiol or an amount of testosterone, and a level at or above a normal level indicates a lack of a need to administer an amount of 17β-estradiol or an amount of testosterone; and wherein the assessing a level of 17β-estradiol and the need to administer an amount of 17β-estradiol are for a female individual, and wherein the assessing a level of free testosterone or total testosterone and the need to administer an amount of testosterone are for a male individual. |
