NEW SOLID FORM OF 1-(2-((2,4-DIMETHYLPHENYL)THIO)PHENYL)PIPERAZINE HYDROBROMIDE

摘要

Title: New Solid Form of 1-(2-((2,4-Dimethylphenyl)thio)phenyl)piperazine Hydrobromide The present invention relates to 1-(2-((2,4-dimethylphenyl)thio)phenyl)piperazine hydrobromide (vortioxetine hydrobromide,a drug for the treatment of depression and anxiety) in amorphous form and in association with an adsorbent. The invention further relates to pharmaceutical compositions comprising amorphous 1-(2-((2,4-dimethylphenyl)thio)phenyl)- piperazinehydrobromidein association with an adsorbent, processes for the manufacture of such pharmaceutical compositions and their use as medicaments.