发明名称 |
Method of forming non-immunogenic hydrophobic protein nanoparticles and uses therefor |
摘要 |
Methods are described for producing non-immunogenic nanoparticles from protein sources by controlling the pH in a nanoprecipitation process. The nanoparticles that are produced by the disclosed methods range in diameter size from about 100 ran to about 400 nm, with a preferred diameter size of from approximately 100 nm to approximately 300 nm, thereby rendering them non- immunogenic. The invention further discloses methods for producing nanoconjugates that are suitable for a variety of therapeutic, diagnostic and other uses. |
申请公布号 |
AU2009244742(B2) |
申请公布日期 |
2014.11.06 |
申请号 |
AU20090244742 |
申请日期 |
2009.05.11 |
申请人 |
SOUTH DAKOTA STATE UNIVERSITY |
发明人 |
PERUMAL, OMATHANU P.;KAUSHIK, RADHEY S.;PODARALLA, SATHEESH K. |
分类号 |
C07K1/14;A61K38/00;B82B3/00;C07K1/02 |
主分类号 |
C07K1/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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